CD55 anticorps (AA 360-410)
Aperçu rapide pour CD55 anticorps (AA 360-410) (ABIN5689937)
Antigène
Voir toutes CD55 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 360-410
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Specificité
- DAF antibody is human specific. At least two isoforms of DAF are known to exist, this antibody will only detect the longest isoform.
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Purification
- DAF antibody is affinity chromatography purified via peptide column.
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Immunogène
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DAF antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DAF.
The immunogen is located within amino acids 360 - 410 of DAF. -
Isotype
- IgG
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Indications d'application
- DAF body can be used for detection of DAF by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- DAF antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- DAF antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- CD55 (Complement Decay-Accelerating Factor (CD55))
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Autre désignation
- DAF
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Sujet
- The decay-accelerating factor (DAF), also known as CD55, is an integral membrane glycoprotein that is involved in the regulation of the complement cascade (1). DAF limits excessive complement activation by accelerating their decay following DAF binding, thereby disrupting the cascade and preventing damage to host cells (2). Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) (3).
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Poids moléculaire
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Predicted: 48 kDa
Observed: 49 kDa -
ID gène
- 1604
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NCBI Accession
- NP_001108224
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UniProt
- P08174
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Pathways
- Système du Complément, Regulation of Leukocyte Mediated Immunity
Antigène
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